


Male pattern baldness (or androgenetic alopecia) is a common condition that affects a significant portion of men as they age. Environmental factors, lifestyle choices, and hormones all play a role in hair loss, it seems genetics are a crucial factor.
There are many types of hair loss, but male pattern baldness is one of the most pervasive. Androgenic alopecia is a hereditary condition, passed down through generations within families. It typically starts as a receding hairline, thinning at the crown of the head, then gradual hair loss between.
Scientists have identified several genes as key players in the development of hair loss in men:
1) Androgen Receptor (AR) Gene:
One of the primary genetic components responsible for male pattern hair loss is the androgen receptor (AR) gene. This gene basically controls the body's response to androgens, which are male sex hormones, including testosterone and dihydrotestosterone (DHT).
When testosterone interacts with the AR gene, it can lead to hair follicles shrinking, resulting in thinner and shorter hair strands. Over time, these miniaturized follicles may cease to produce hair, leading to baldness.
2) 5-Alpha Reductase Genes:
Another set of genes involved in male pattern hair loss are the 5-alpha reductase genes, specifically the SRD5A1 and SRD5A2 genes. These genes encode enzymes responsible for converting testosterone into dihydrotestosterone (DHT) within hair follicles. DHT can shrink hair follicles, leading to the gradual reduction in hair thickness and density.
3) Other Contributing Genes:
While the AR and 5-alpha reductase genes affect male pattern hair loss, other genetic factors may also come into play. Research suggests that other genes involved in hair growth and development could influence why hair loss occurs.
Family history is a crucial factor in understanding the genetic basis of male pattern hair loss. If close male relatives (your father, grandfather, or brothers) experienced male pattern baldness, you are more likely to as well. Because these genes come from both parents, their combined genetic influence significantly increases the risk of hair loss.
Most men experience the first signs of balding in their late 20s or early 30s. In some cases, signs can start in their late teens. By age 50, most men will have already noticed thinning in the classic areas of the scalp.
Understanding the genetic components of male pattern hair loss has led to the development of various treatment options. These treatments aim to counteract the effects of genetic factors and promote hair growth. Some common approaches include:
Genetic factors are the primary drivers of male pattern hair loss. Key genes such as the androgen receptor (AR) gene and 5-alpha reductase genes play crucial roles in its development. Understanding these genetic components is essential for both identifying the risk of male pattern baldness and developing effective treatments.
While you cannot change your genetic predisposition to male pattern baldness, you can take steps to reduce its impact:
While genetics may predispose people to hair loss, options are available to treat and restore a fuller head of hair. At Dr. Yates Hair Science, we can provide personalized guidance on managing your male pattern hair loss. Call us today to set up your free consultation appointment!
Ready to love your hair? Call 312.883.9617 for a consultation or fill out the form below
OUR LOCATION
213 N. Stetson Ave
Chicago, IL 60601
HOURS
Copyright ©2025 Dr. Yates Hair Science | All Rights Reserved
Powered by HEAVY LEVITY